Mumwe muongorori wekuFrance azivisa nezvengozi dzetsono dzakapinza mumarabhoritari mushure metsaona inotyisa inosanganisira kubuda kwemvura inonyungudutsa nguva dzose. Iye zvino ari kukumbira kuti pave nekugadzirwa kwetsono dzinotsiva dzinonyungudutsa kana kuti ma reagents kuti pave nekuchengetedzeka mumarabhoritari. 1
Muna Chikumi 2018, mudzidzi ane makore makumi maviri nemaviri ekuberekwa Nicolas aishanda murabhoritari yaSebastien Vidal paYunivhesiti yeLyon 1. Akadurura sirinji yedichloromethane (DXM) muflask ndokubaya chigunwe chake netsaona. Vidal akaverenga kuti madonhwe maviri kana pasi pe100 microliters eDXM akasara mutsono ndokupinda mumunwe.
Mifananidzo yakatevedzana inoratidza zvakazoitika - chinyorwa chemagazini chinonyevera kuti vamwe vangawana mifananidzo (iri pazasi) ichivhiringidza. Anenge maminetsi gumi nemashanu mushure mekubayiwa netsono, Nicolas akaita donda repepuru pamunwe wake. Maawa maviri gare gare, mipendero yemaplaque epepuru yakatanga kusviba, zvichiratidza kutanga kwekufa kwemasero - kufa kwemasero. Panguva iyi, Nicholas akanyunyuta kuti minwe yake yaipisa uye aisakwanisa kuifambisa.
Nicholas aida kuvhiyiwa nekukurumidza kuti achengetedze chigunwe chake. Vanachiremba vekuvhiya, avo pakutanga vaifunga kuti aizofanira kuchekwa, vakakwanisa kubvisa ganda rakafa rakatenderedza ronda rekubaiwa ndokugadzirazve chigunwe vachishandisa ganda rakabva muruoko rwaNicholas. Chiremba uyu akazoyeuka kuti mumakore ake makumi maviri nemashanu achishanda mumakamuri ekukurumidzira, akanga asati amboona kukuvara kwakadaro.
Minwe yaNicholas yava kuda kudzokera pakare, kunyange hazvo kuridza kwake gitare kwairwadza nechirwere chakakanganisa tsinga dzake, zvichideredza simba rake nehunyanzvi hwake.
DCM ndeimwe yezvinonyungudutsa zvinoshandiswa zvakanyanya mumarabhoritari emakemikari ekugadzira. DCM Injury Information pamwe neMaterial Safety Data Sheet yayo (MSDS) zvinopa ruzivo nezvekutarisana kwemaziso, kusangana kweganda, kumedzwa uye kufemereka, asi kwete pakubaiwa jekiseni, Vidal akadaro. Munguva yekuferefeta, Vidal akawana kuti chiitiko chakafanana chakaitika muThailand, kunyangwe murume uyu akazvibaya jekiseni re2 milliliters redichloromethane, mhedzisiro yacho yakashumwa muchipatara cheBangkok.
Nyaya idzi dzinoratidza kuti mafaira eMSDS anofanira kuchinjwa kuti asanganisire ruzivo rwakabatana nemaitiro eparenteral, akadaro Vidal. “Asi mukuru wezvekuchengetedza payunivhesiti yangu akandiudza kuti kugadzirisa mafaira eMSDS kwaizotora nguva yakareba uye kunoda data rakawanda kuti riunganidzwe.” Izvi zvaisanganisira zvidzidzo zvakadzama zvemhuka kuti zvidzokorore tsaona yacho, kuongorora kukuvara kwenyama, uye kuongororwa kwechiremba.
Zvigunwe zvevadzidzi zviri muzvikamu zvakasiyana-siyana mushure mekubayiwa netsaona kwehuwandu hushoma hwemethylene chloride. Kubva kuruboshwe kuenda kurudyi, maminetsi gumi kusvika gumi nemashanu mushure mekukuvara, wozotevera maawa maviri, maawa makumi maviri nemana (mushure mekuvhiyiwa), mazuva maviri, mazuva mashanu, uye gore rimwe (mifananidzo yese iri pazasi)
Zvichitevera kushomeka kweruzivo nezvekushandiswa kweDCM, Vidal anotarisira kuti nyaya iyi ichaparadzirwa zvakanyanya. Mhinduro dzakanaka. Akati gwaro iri [rakaparadzirwa zvakanyanya]. "Vakuru vezvekuchengetedza kubva kumayunivhesiti ekuCanada, US neFrance vakandiudza kuti vaizoisa nyaya iyi muzvidzidzo zvavo. Vanhu vakatitenda nekugovana nyaya iyi. Vazhinji havana kuda kutaura nezvazvo vachitya kuziviswa zvisina kunaka [kwesangano ravo] Asi masangano edu ave achitsigira zvikuru kubva pakutanga uye achiri kutsigira.
Vidal anodawo kuti vesainzi nevatengesi vemakemikari vagadzire nzira dzakachengeteka uye mimwe michina yekushandisa nguva dzose senge kutamisa makemikari. Imwe pfungwa ndeyekushandisa tsono "yakatsetseka" kudzivirira maronda ekuboorwa. "Idzi dziripo izvozvi, asi tinowanzo shandisa tsono dzakapinza mumakemikari echisikigo nekuti tinoda kuisa zvinonyungudutsa kuburikidza nezvinodzivirira rabha kudzivirira midziyo yedu yekudzivirira kubva kumhepo/hunyoro hwekunze. Tsono "dzakatsetseka" hadzigone kupfuura nemuzvinodzivirira rabha. Uyu hausi mubvunzo uri nyore, asi pamwe kukundikana uku kuchatungamira kune mazano akanaka.
Alain Martin, maneja wehutano nekuchengetedzeka paDhipatimendi reChemistry reYunivhesiti yeStrathclyde, akati haasati amboona tsaona yakadaro. "Murabhoritari, masirinji ane tsono anowanzo shandiswa, asi kana kunyatsorongeka kwakakosha, saka kushandisa micropipettes kungave sarudzo yakachengeteka," anowedzera, zvichienderana nekudzidziswa, senge kusarudza matipi uye kushandisa mapipettes nemazvo. "Vadzidzi vedu vari kudzidziswa kubata tsono nemazvo here, kuisa nekubvisa tsono here?" akabvunza. "Pane anofunga kuti chii chimwe chingashandiswa? Pamwe kwete.
2 K. Sanprasert, T. Thangrongchitr naN. Krairojananan, Asia. Pack. J. Med. Toxicology, 2018, 7, 84 (DOI: 10.22038/apjmt.2018.11981)
Mari inosvika mamiriyoni mazana maviri negumi kubva kuModerna muzvinabhizinesi uye mudyari mari Tim Springer yekutsigira tsvakiridzo iri kuenderera mberi
Kusanganiswa kwekuyedza kweX-ray diffraction uye simulations zvinoratidza kuti chiedza chelaser chakasimba chinogona kushandura polystyrene.
© Royal Society of Chemistry document.write(new Date().getFullYear()); Nhamba yekunyoresa yerubatsiro: 207890