Hakuna mushonga wechirwere cheAlzheimer, asi masayendisiti anogara achitsvaga nzira dzekurapa zviratidzo zvechirwere ichi.
Vaongorori vari kushandawo pakutsvaga chirwere cheAlzheimer's nekukurumidza, sezvo kuchiwanikwa nekukurumidza kuchibatsira pakurapwa.
Chidzidzo chitsva chakaburitswa muFrontiers in Aging Neuroscience chinoratidza kuti uroformic acid inogona kuva chiratidzo chekuongorora chirwere cheAlzheimer's nekukurumidza.
Sangano reU.S. Centers for Disease Control and Prevention (CDC) rinotsanangura chirwere chepfungwa se "kukanganisika kwendangariro, kufunga, kana kuita sarudzo kunovhiringidza mabasa ezuva nezuva."
Kuwedzera kuchirwere cheAlzheimer's, kune mamwe marudzi echirwere chedementia akadai sedementia ine Lewy bodies uye vascular dementia. Asi chirwere cheAlzheimer's ndicho chinonyanya kukonzera dementia.
Sekureva kwemushumo we2022 weAlzheimer's Disease Association, vanhu vanosvika mamiriyoni matanhatu nehafu muUnited States vari kurarama nechirwere ichi. Pamusoro pezvo, vaongorori vanotarisira kuti huwandu ihwohwo huchapetwa kaviri panosvika gore ra2050.
Pamusoro pezvo, vanhu vane chirwere cheAlzheimer chakanyanya kukura vanogona kunetseka nekumedza, kutaura, uye kufamba.
Kusvika pakutanga kwema2000, kuongororwa kwechitunha ndiyo chete nzira yekusimbisa kana munhu aine chirwere cheAlzheimer kana chimwe chimiro chedementia.
Sekureva kweNational Institute on Aging, vanachiremba vava kukwanisa kubhooresa lumbar, inozivikanwawo se lumbar puncture, kuti vaongorore zviratidzo zvine chekuita nechirwere cheAlzheimer.
Vanachiremba vanotsvaga zviratidzo zve biomarker zvakaita se beta-amyloid 42 (chinhu chikuru che amyloid plaques muuropi) uye vanogona kutsvaga zvisina kunaka paPET scan.
"Maitiro matsva ekutora mifananidzo, kunyanya mifananidzo yeamyloid, mifananidzo yePET amyloid, uye mifananidzo yetau PET, anotibvumira kuona zvisizvo muuropi munhu achiri mupenyu," akadaro purofesa weMichigan Public Health uye chiremba Kenneth M., Dr. Langa. MuAnn Arbor, uyo asina kubatanidzwa muchidzidzo ichi, akataura nezvepodcast yeMichigan Medicine ichangoburwa.
Kune nzira dzakasiyana-siyana dzekurapa dziripo dzekubatsira kuderedza kuoma kwezviratidzo zveasthma uye kuderedza kufambira mberi kwechirwere, kunyange hazvo dzisingakwanise kuchirapa.
Semuenzaniso, chiremba anogona kunyora mishonga yakaita sedonepezil kana galantamine kuderedza zviratidzo zveasthma. Mushonga wekuongorora unonzi lecanemab unogona zvakare kunonotsa kufambira mberi kwechirwere cheAlzheimer.
Nekuti kuongororwa kwechirwere cheAlzheimer kunodhura uye kungasawanikwa nemunhu wese, vamwe vaongorori vari kukoshesa kuongororwa kwekutanga.
Vatsvaguriri vekuShanghai Jiao Tong University neWuxi Institute of Diagnostic Innovation muChina vakaongorora pamwe chete basa reformic acid sechiratidzo chechirwere cheAlzheimer muweti.
Masayendisiti akasarudza chinhu ichi zvichibva pakutsvagurudza kwavo kare nezvechirwere cheAlzheimer's. Vanoti kushandiswa kwe formaldehyde zvisina kujairika chinhu chikuru chinokonzera kukanganisa kwepfungwa kunokonzerwa nekukwegura.
Pachidzidzo ichi, vanyori vakatora vanhu 574 kubva kuMemory Clinic yeSixth People's Hospital yeShanghai, China.
Vakakamura vatori vechikamu mumapoka mashanu zvichienderana nekushanda kwavo pabvunzo dzekushanda kwepfungwa; mapoka aya aitangira pakuziva zvakanaka kusvika kuAlzheimer's:
Vaongorori vakatora sampuro dzeweti kubva kune vaitora chikamu kuti vaone huwandu hweasidhi yefomu uye sampuro dzeropa kuti vaongorore DNA.
Nekuenzanisa mazinga e formic acid muboka rega rega, vaongorori vakadzidza kuti paive nemusiyano pakati pevatori vechikamu vane hutano hwepfungwa nevaya vaive vasina simba rakakwana.
Boka raiva nedambudziko rekuziva raiva nehuwandu hwakawanda hwe formic acid muweti kupfuura boka raiva neutano hwakanaka.
Pamusoro pezvo, vanhu vane chirwere cheAlzheimer vaive nehuwandu hwakawanda hwe formic acid muweti yavo kupfuura vanhu vane hutano hwakanaka.
Masayendisiti akawanawo kuti huwandu hweasidhi yemuweti hwakabatana zvakasiyana nekuyedzwa kwepfungwa mukurangarira nekucherechedza.
"Mazinga emudumbu wemuweti akakwira zvakanyanya muboka rekuongorora [kuderera kwekuziva kwepfungwa], zvinoreva kuti mudumbu wemuweti unogona kushandiswa pakuongorora chirwere cheAlzheimer nekukurumidza," vanyori vanonyora kudaro.
Zvakabuda muchidzidzo ichi zvakakosha nekuda kwezvikonzero zvakati wandei, kunyanya kudhura kwakanyanya kwekuongorora chirwere cheAlzheimer.
Kana tsvakiridzo yakawedzerwa ikaratidza kuti uric acid inogona kuona kudzikira kweruzivo rwemuviri, izvi zvinogona kuva bvunzo iri nyore kushandisa uye inodhura zvishoma.
Pamusoro pezvo, kana bvunzo yakadaro ikakwanisa kuona kudzikira kwepfungwa kunokonzerwa nechirwere cheAlzheimer, nyanzvi dzezvehutano dzinogona kupindira nekukurumidza.
Dr. Sandra Petersen, DNP, mutevedzeri wemutungamiri mukuru wehutano nekugara zvakanaka kuPegasus Senior Living, vakataura nezvechidzidzo ichi mubvunzurudzo neMedical News Today:
"Kuchinja kwechirwere cheAlzheimer kunotanga makore angangoita makumi maviri kusvika makumi matatu chirwere chisati chaonekwa uye kazhinji hakuonekwi kusvika paitika kukuvara kukuru. Tinoziva kuti kuonekwa nekukurumidza kunogona kupa varwere nzira dzakawanda dzekurapa uye kugona kuronga kurapwa mune ramangwana."
"Kubudirira mubvunzo iyi (isingakuvadzi uye isingadhuri) inowanikwa kune veruzhinji kuchachinja zvinhu mukurwisa chirwere cheAlzheimer," akadaro Dr. Peterson.
Masayendisiti munguva pfupi yapfuura akawana chiratidzo chebiomarker chinogona kubatsira vanachiremba kuongorora chirwere cheAlzheimer pakutanga. Izvi zvichabvumira vanachiremba…
Mhedzisiro yechidzidzo chitsva mumakonzo rimwe zuva inogona kubatsira kugadzira bvunzo yeropa iyo ichava chikamu chekuongororwa kwechirwere cheAlzheimer nedzimwe mhando dze…
Chidzidzo chitsva chinoshandisa PET brain scans kufanotaura kudzikira kwekuziva zvichibva pakuvapo kwemapuroteni e-amyloid ne tau muuropi, zvikasadaro kuziva…
Vanachiremba parizvino vanoshandisa bvunzo dzakasiyana-siyana dzekuziva uye scans kuti vaone chirwere cheAlzheimer. Vatsvaguri vakagadzira algorithm inogona kushandiswa pane imwe…
Kuongororwa kwemaziso nekukurumidza kunogona kupa ruzivo rwakakosha nezve hutano hwehuropi rimwe zuva. Zvikuru sei, kunogona kuona zviratidzo zve dementia.